Snake Venom Proteins Isolated from Tunisian Vipers: Pharmacological and Therapeutic Overview

: The venoms of Tunisian wildlife snakes are complex mixtures containing proteins/ peptides and non-protein molecules. Proteins the most abundant compounds responsible for biological effects venoms. Snake proteins have enzymatic or nonenzymatic activities, which grouped into different families, including C-type lectin proteins, disintegrins (long, medium short disintegrins), Kunitz-type serine protease inhibitors, natriuretic- like peptides, vascular endothelial growth factor-related L-amino acid oxidases, phospholipases A2 proteinases. With technological advancements, toxic were turned potential benefits clinical diagnosis, basic research development new tools drugs use. Our team has shown that Macrovipera lebetina Cerastes cerastes venom components had great treatment cancer, angiogenesis disorders cardiovascular diseases. This review is an overview snake from their biochemical, pharmacological molecular characterization importance as protein resources with therapeutic potential.